Using proven, evidence-based interventions to help individuals who struggle with depression. Call us today to find out if ketamine or esketamine is right for you.
The Ketamine Service at McLean Hospital offers specialized treatment for adults struggling with depression, especially major depressive disorder and bipolar disorder.
Our data-driven, evidence-based service applies cutting-edge research to clinical practice. We create personalized treatments based on thorough, scientific evaluation of each patient.
Although it has been used for years as an anesthetic, ketamine has been shown to be a highly effective treatment for many individuals who struggle with severe depression.
In addition, those who are experiencing symptoms that are threatening their health or safety may be good candidates for ketamine, which can often work more quickly than other treatments.
Our dedicated treatment team includes psychiatrists and nursing staff who have both medical and psychiatric training. Staff are uniquely equipped to assist our patient population and ensure that treatments are administered in the safest manner possible.
We offer two types of ketamine therapy. Our services are available as outpatient treatments or as a component of inpatient care:
- On our Belmont campus, we provide IV ketamine infusion and intranasal esketamine administration
- On our Oak Street location in Middleborough, we offer intranasal esketamine treatment
Ketamine infusions are delivered via intravenous (IV) procedure over 40 minutes. Patients remain awake during the treatment. Many individuals opt to read, listen to music, or just relax. Patients are monitored before, during, and after the treatment according to evolving standards of best and safe practice.
Esketamine (Spravato) is FDA approved for the treatment of patients who struggle with major depressive disorder. People who receive esketamine are also on other antidepressant medications.
Esketamine is self-administered intranasally under the supervision of a nurse. Patients are also monitored before, during, and after this treatment. Our procedures are in line with the FDA-mandated REMS reporting system.
McLean’s Ketamine Service is available in two locations. In Belmont on McLean’s main campus, the service is located within the ECT/TMS suite in the de Marneffe Building. In Middleborough, the Neurotherapeutics Suite is at our Oak Street site.
Ketamine and esketamine have been shown to be effective interventions for severe depression, with or without anxiety, particularly for individuals who have struggled with standard therapies.
In recent years, research efforts and reports from ketamine clinics have demonstrated success in using these drugs to quickly and effectively address severe depression.
At McLean, ketamine and esketamine are used to help depressed individuals who have not responded to at least two courses of medications most often prescribed for depression. They can also help individuals who are experiencing acute suicidal thoughts or behaviors and who would benefit from a fast-acting intervention.
It is important to note that ketamine therapies should never be considered as a replacement for psychiatric admission for patients who may be a danger to themselves or others.