Diego Pizzagalli Related Content

Depression has become the leading cause of disability worldwide across all illnesses, according to the World Health Organization. In only a single year, 264 million people deal with depression , and 800,000 lives are lost to suicide . Yet psychiatrists are often forced to resort to a trial-and-error...

GrayMatters Health , a digital therapeutics start-up company, announced that the BIRD Israel-U.S. Binational Industrial Research and Development Foundation awarded a grant to McLean Hospital and the company to develop a novel solution for the therapy of major depressive disorder (MDD) with anhedonia...

With a $15,973,571, five-year grant from the National Institute of Mental Health (NIMH), investigators from McLean Hospital and four other institutions will further their studies into the brain mechanisms behind depression and anxiety. Under the title “Novel Treatment Targets for Affective Disorders...

McLean Hospital’s Diego A. Pizzagalli, PhD , has been named editor of the journal Cognitive, Affective, & Behavioral Neuroscience (CABN). Pizzagalli’s tenure as editor begins on January 1, 2021. Published six times each year, the publication presents empirical articles and reviews on behavior and...

How do you predict which teenagers will develop clinical depression ? Can you use brain activity, mood or behavior patterns, and other information? Are there targeted prevention strategies that could stop a vulnerable young person from plunging into depression? And for teenagers who are currently...

McLean Hospital and Harvard Medical School researchers believe they have uncovered a method that could be useful in predicting a depressed patient’s treatment prognosis, prior to starting treatment. In the paper “ Pretreatment Rostral Anterior Cingulate Cortex Activity in Relation to Symptom...

On December 4, 2017, the American College of Neuropsychopharmacology (ACNP) honored McLean Hospital’s Diego A. Pizzagalli, PhD , with the 2017 Joel Elkes Research Award. The ACNP presents this annual award in recognition of a scientist’s outstanding clinical contribution to neuropsychopharmacology...

Major depressive disorder (MDD) affects about 7% of people in the United States each year. Although researchers and clinicians know that stressful life events can trigger a depressive episode, the biological mechanisms behind it are not well understood. Studies led by Diego A. Pizzagalli, PhD...

Since its invention more than 40 years ago, magnetic resonance imaging (MRI) technology has allowed clinicians and researchers to produce more precise images of the human body and gain a greater understanding of injuries and disease. For McLean’s Scott E. Lukas, PhD, and Diego A. Pizzagalli, PhD...

Scott E. Lukas, PhD , director of the McLean Imaging Center (MIC), can barely contain his excitement when describing McLean’s new 3 Tesla Siemens PRISMA MRI scanner. An extraordinary $3.75M grant from the Manton Foundation funded this state of the art acquisition. According to Lukas and fellow MIC...

For much of the last century, depression has been viewed largely as a single disease; however, it is an extraordinarily heterogeneous condition. Consequently, predicting which healthy people will develop depression is challenging. Given that approximately half of patients do not respond to current...

One researcher is looking at how administering xenon gas may minimize injury to a traumatized brain. Another is studying how childhood sexual abuse affects brain function and increases the risk of re-victimization. A third is trying to understand the connection between early tobacco use and later...

The future of brain science lies in researchers like Poornima Kumar , a 30-year-old neuroscientist with the mind of a mathematician, the expertise of an engineer, and a PhD in neuroimaging. Kumar, the hospital’s first John and Charlene Madison Cassidy Fellow in Translational Neuroscience, works in...

Depression, anxiety, and stress are a debilitating triad. About one in six Americans will suffer from depression at some point in his or her life; one in four will struggle with an anxiety disorder. Often, the two go hand in hand, triggered by stressors like childhood neglect or the death of a loved...